For patients who have been diagnosed with sclerofibroma, the main concern is how to treat it. Since sclerofibroma is a benign tumor, can it be cured without surgery? Is radiation therapy okay? Today we will talk about the treatment of sclerofibroma. First of all, it needs to be clear that surgery is the most important treatment for sclerofibroma. For patients diagnosed with sclerofibroma for the first time, if a complete, radical and extensive resection can be performed, and at the same time, the surgery will not cause too much damage to the body (e.g., damage to limb function, etc.), surgery is preferred in this case. Because sclerofibromas are not life-threatening, they do not require radical resection at the expense of limb function, unlike malignant tumors in general. Radiotherapy may be considered when the tumor is not resectable or when resection would result in severe dysfunction. In addition, when the tumor is resected, if there are still lesions remaining in the surrounding area, radiotherapy is also needed at this time. However, it is worth noting that radiotherapy has some limitations on the age of patients. It is generally believed that radiotherapy is not effective in patients with sclerofibrosarcoma under 30 years of age, and the efficacy is relatively better in patients over 30 years of age. The reason why radiotherapy is not recommended for young patients or pediatric patients is mainly to consider that radiotherapy may cause delayed complications to this kind of people, which are mainly the following three kinds: 1, limb contracture: radiotherapy will lead to muscle atrophy, deformation of joints, which in turn will cause limb dysfunction. 2, growth and developmental disorders: children with sclerofibroma in growth and developmental period, choosing radiotherapy may lead to developmental abnormalities. For example, if the sclerofibroma grows on the child’s leg and receives radiotherapy after surgery, the leg is likely to stop growing after that, and the two legs will be unequal in length after a long period of time; 3, induce malignant transformation: sclerofibroma is a kind of benign tumor, but if the tumor cells are stimulated by the radiotherapy, the patient may grow malignant tumors, such as fibrosarcoma, after 10 years. Therefore, for young patients with sclerofibroma, radiotherapy should be chosen with great caution. Then, what should be done for patients who can neither have surgery nor radiotherapy? At this point, drug therapy can be considered. Currently, there are three most common types of drug therapy: chemotherapy, anti-estrogen therapy, and targeted therapy. The literature reports that chemotherapy is the most effective, followed by targeted therapy, and anti-estrogen therapy is the least effective. If the patient is not sensitive to the drug, or develops drug resistance after using the drug, and some patients are not willing to accept the drug treatment, conservative treatment can be carried out at this time. However, the conservative treatment of hard fibroids is not to do acupuncture, physical therapy, massage and so on. On the contrary, these measures will, to a certain extent, stimulate the tumor and even cause tumor malignancy. Therefore, it is recommended that patients with hard fibroid tumor should never try it. So, what is the conservative treatment for sclerofibrosarcoma? In fact, it is to “wait and see” how the tumor grows. Since sclerofibroma is a benign tumor that is not fatal, if the tumor grows slowly or is in a stagnant stage, then there is no need to worry too much. However, if the tumor is still growing rapidly, the patient needs to understand the pros and cons of treatment and discuss the treatment options with the doctor. Generally speaking, sclerofibromas located in the abdominal and pelvic cavities grow in a way that is more similar to malignant tumors and require prompt treatment; sclerofibromas located in the limbs and trunks can continue to be observed for growth and size if the patient is unwilling to undergo treatment and the tumor is found not to be growing fast.