There are many ways to treat primary liver cancer, but none of them can be universally applied to every patient, and a single method is rarely used to treat liver cancer in clinical practice. Various methods need further research and improvement. Minimally invasive treatment is an emerging treatment method in recent years, which is widely promoted for its small trauma, low pain and good efficacy, and the treatment effect can reach or even exceed that of traditional surgery. 1.Vascular interventional therapy: Among liver cancer, vascular interventional therapy has the most clinical applications. It is mainly selective hepatic artery perfusion therapy, selective hepatic artery embolization and selective hepatic artery chemoembolization. The blood supply of primary hepatocellular carcinoma is 90%-95% from the hepatic artery, which provides the anatomical basis for vascular interventional treatment of tumors in hepatocellular carcinoma. A small incision of about 2-3mm is punctured on the skin, and a tube is inserted from the artery to the blood supply artery of hepatocellular carcinoma, and then the drug is administered through the catheter, which can increase the local drug concentration of tumor cells and prolong the contact time between the drug and the lesion, and reduce the total drug dose of the whole body, so as to improve the efficacy and reduce side effects. And it can also create the opportunity of secondary surgery for patients. 2.Ablation therapy: CT or B-ultrasound guided radiofrequency ablation, chemical ablation therapy; under the guidance of CT or B-ultrasound, radiofrequency needle is punctured into the liver tumor through the skin, and physical heating or chemical action is performed to necrotize the tumor.