Ankylosis, or ankylosing spondylitis, can be treated aggressively at an early stage to bring the disease to a stable stage, and the disease can be kept from progressing in most patients, although progression of the disease may occur. The cause of ankylosing spondylitis is still unclear, with family aggregation, possibly related to autoimmunity. The typical symptom of ankylosing spondylitis is pain in the sacroiliac joints, which may not be manifested in the early stage or may be manifested as iridocyclitis, low back pain, etc. The principle of treatment is early diagnosis and early treatment. The principle of treatment is early diagnosis and early treatment. Therefore, once diagnosed with ankylosing spondylitis, one should take appropriate exercise under the guidance of the doctor, take non-steroidal anti-inflammatory drugs, and in severe cases, biologics can be used, and undergo regular review. In general, it is important to sleep on a hard bed, try to sleep flat, and maintain a positive mindset. Early and active treatment can make the disease reach a stable stage and stop progressing, but if no measures are taken, when the disease develops to joint ankylosis or deformity of the spine, it will not be relieved, and even cause disability, affecting the quality of life.