Symptoms: Early stage liver cancer often has no specific symptoms, while the symptoms of middle and late stage liver cancer are more. Signs: Early stage hepatocellular carcinoma often has no obvious positive signs or only resembles the signs of cirrhosis. In middle and late stage liver cancer, signs such as liver enlargement, jaundice and ascites usually appear. In addition, those with combined cirrhosis often have liver palms, spider nevus, enlarged male breast, lower limb edema, etc. When extrahepatic metastasis occurs, signs corresponding to each metastatic site may appear. Complications: common ones include upper gastrointestinal bleeding, hepatocellular carcinoma rupture bleeding, hepatic and renal insufficiency, etc. Primary hepatocellular carcinoma examination: serum alpha-fetoprotein (AFP) assay, radioimmunoassay for continuous serum AFP ≥400μg/L, provided that pregnancy and imaging examination are excluded: 1. 2.CT examination: with high resolution, the diagnostic rate can reach more than 90%, and can detect microscopic cancer foci of 25px in diameter. 3.MRI examination: Its diagnostic value is similar to CT, and it is better than CT in differentiating benign and malignant intrahepatic occupying lesions, especially from hemangioma. 4.Selective abdominal artery or hepatic arteriography: For carcinoma with abundant blood vessels, its resolution is limited to about 25px, and its positive rate can reach 90% for small hepatocellular carcinoma <50px< span="">. 5. Needle aspiration cytology by liver aspiration: fine needle aspiration under B-type ultrasound or CT guidance can help improve the positive rate.