How to treat liver cancer with Chinese medicine? Primary liver cancer is the most common malignant tumor in clinical practice and is called the “king of tumors”. Without early detection and complete surgical resection, the overall 5-year survival rate of liver cancer patients does not exceed 5%, so in addition to advocating early detection, early diagnosis and early treatment, it is more important to explore more effective treatment methods to improve the prognosis of liver cancer patients. Therefore, besides advocating early detection, early diagnosis and early treatment, it is more important to explore more effective treatment methods. Chinese medicine plays an important role in the treatment of liver cancer, and the combined treatment of Chinese and Western medicine has become an important means of liver cancer treatment. In recent decade, with the development of molecular biology technology, a lot of research has been done on the mechanism of Chinese medicine in the treatment of liver cancer. I. Direct anti-tumor effects Pharmacological experiments have proved that many traditional Chinese medicines have direct anti-tumor effects in themselves, whether in compound or single Chinese medicines, and some of them have relatively good effects on liver cancer, such as Lonicera japonica, Curcuma longa, Curcuma longa, Trigonella spp. Apoptosis. Apoptosis is one of the important mechanisms to maintain the stability of body environment and normal physiological functions of tissues and organs, and the formation of tumor is closely related to the blockage of apoptosis. 2. Inhibition of cancer cell proliferation and induction of differentiation. Cell proliferation caused by uncontrolled cell cycle is an important cause of carcinogenesis. Inhibition of liver cancer cell proliferation is one of the important research directions in the treatment of liver cancer. Regulation of immune function The immune status of the body is closely related to the development, recurrence and survival of tumor, and strengthening the anti-tumor immune function of the body is one of the important mechanisms of Chinese medicine against tumor. The growth and metastasis of malignant tumors must rely on neovascularization to provide sufficient nutrition in order to achieve. Therefore, in recent years, anti-tumor angiogenesis has become a hot spot for basic and clinical research on tumor treatment, and is the most promising target for tumor-directed therapy. IV. Reversal of drug resistance Tumor cells are resistant to chemotherapeutic drugs, which is one of the main reasons for the failure of tumor chemotherapy. Therefore, it is important to find chemotherapy sensitizers with reversal of drug resistance and little adverse effects to improve tumor treatment. Many drugs have been found to inhibit the function of P-glycoprotein (P-gP) and reverse drug resistance, but they mostly have large adverse effects. Chinese medicine has a long history and rich experience in treating liver cancer, and it should be possible to screen out low-toxicity multidrug resistance reversal agents from them. In recent years, the research of liver cancer has been a hot spot in tumor research. Chinese medicine has even conducted a lot of scientific research in the treatment of liver cancer and its mechanism, and has made certain achievements. Chinese medicine can achieve the purpose of treating the disease by inhibiting the growth of liver cancer cells, inhibiting their proliferation, promoting cell differentiation and apoptosis, inhibiting recurrence and metastasis, or enhancing the immune function of the body. Although the efficacy of Chinese medicine in killing tumors is less than that of chemotherapeutic drugs, its multi-targeted comprehensive effect ensures that the drugs continue to be effective for a long time, prolonging the survival time with tumors and improving patients’ quality of life. For example, Jianshuanyi Kidney Granules and Fuzheng Dissipative Capsules from the Chinese Academy of Traditional Chinese Medicine are Chinese medicines with proven clinical efficacy in the treatment of liver cancer, which, combined with western medical treatments, can increase the efficacy and reduce toxicity, reduce patients’ symptoms and improve survival quality. The combination with western medical treatments can increase the effectiveness and reduce the toxicity, reduce the symptoms and improve the survival quality.