Benign thyroid nodules are generally not painful because they are slow growing and are not invasive to the surrounding organs, and because they are small and rarely compress the surrounding organs and pull on the thyroid peritoneum, they are rarely painful. However, a perennial thyroid nodule may be painful if it is large and puts pressure on the surrounding organs. However, benign thyroid nodules have distinctive features on ultrasound. Benign thyroid nodules have clear margins, clear borders, relatively homogeneous internal echogenicity, and no abundant blood flow, but the diagnosis of benign and malignant thyroid nodules ultimately depends on pathology.