LSIL is a low-grade squamous intraepithelial lesion and is not a cervical cancer. However, there are similarities with the causes of cervical cancer, both of which can be caused by HPV infection. LSIL is a pathological change that occurs in the cervix, vagina, or vulva after a woman is infected with HPV and the appearance of corresponding symptoms, such as vulvar itching, skin breakdown, and ulcers; some patients have no symptoms or only manifest as papules, spots, or papillary warts in the vulvar area. Although HPV infection can cause cervical cancer, only a very small percentage (about 1%) of patients will develop cervical cancer. In some patients, HPV infection first causes lesions in the cervix, vagina or vulva. When lesions occur in the area covering the squamous epithelium, they are called squamous intraepithelial lesions; when the lesions are mild, they are called low-grade squamous intraepithelial lesions, or LSIL. Treatment of LSIL is simple because in most cases, HPV can be cleared by the body’s immune system, so LSIL Most of the time, LSIL regresses on its own, and asymptomatic patients do not need special treatment and can be reviewed regularly. Patients with symptoms can recover with topical medication or laser treatment. However, if there is no self-limitation and no corresponding treatment, the lesion will continue to develop and eventually lead to cancer.