Nephrolithiasis is a common disease in nephrology and is not a major disease. If nephritis is not actively treated with a decline in kidney function, eventually leading to uremia is a major disease. Acute nephritis is divided into acute nephritis and chronic nephritis, acute nephritis without special treatment, that is, bed rest and symptomatic treatment treatment, can be self-healing, some patients turned to chronic nephritis. Chronic nephritis is a group of chronic nephritis syndrome with clinical manifestations of hematuria, proteinuria, edema and hypertension. Chronic nephritis is to actively control blood pressure and reduce proteinuria. If proteinuria >1g/24h, blood pressure should be controlled below 125/75mmHg. If proteinuria <1g/24h, blood pressure should be controlled below 130/80mmHg, and active improvement of examination, with kidney biopsy indications suggest kidney biopsy, clear pathological type, determine the prognosis, guide the treatment, and choose hormone and immune agent treatment. Chronic nephritis is a chronic progressive disease until the end stage of renal failure, that is, the uremic phase, which requires renal replacement therapy, such as hemodialysis or peritoneal dialysis treatment, and active treatment of various complications of uremia, correction of anemia, control of blood pressure, correction of low calcium, high phosphorus, hyperparathyroidism, and active control of infection.