Nodular acne, in fact, is clinically referred to as “nodular acne”, which occurs on the face or chest and back, and may lead to abscesses and nodular cystic acne if left unchecked. 1. Topical medications: Commonly used are peroxymethylphenidate gel, adapalene gel, fusidic acid ointment, retinoic acid ointment, and clindamycin ointment. Before applying the drug, you need to clean the lesions; 2, oral drugs: commonly used tetracycline antibiotics, such as doxycycline, minocycline, can also take oral retinoids, such as isotretinoin capsules. You can also take oral Chinese medicine, such as Feng Feng Tong Sheng Granules, Gentian Diarrhea Liver Pills and Blood Transfusion Capsules, etc.; 3, local injection drugs: for patients who do not have good results with oral and conventional topical drugs, you can also locally inject glycocorticoids such as prednisone, and antibiotics such as gentamicin to shrink the nodules, accelerate the inflammatory damage and relieve clinical symptoms. In addition, you need to pay attention to the usual routine of life, not to stay up late, and greasy, spicy, stimulating food to avoid eating.