Pleural effusion has just been pumped and there is water again, it needs to be treated according to the etiology, mainly including tuberculous pleurisy, pneumonia, lung cancer, etc. Conservative treatment and surgical treatment can be taken to control the condition. 1. Tuberculous pleurisy: mainly due to the pleural effusion caused by infection of tuberculosis bacillus, it needs anti-tuberculosis treatment as soon as possible, clinically available isoniazid, rifampicin, streptomycin and so on. If the condition is serious or in the consolidation period, it can be combined with two kinds of anti-tuberculosis drug treatment. 2. Pneumonia: bacterial pneumonia is more common, antibiotic treatment can be chosen according to the result of sensitivity test, such as cephalosporin, penicillin, doxycycline and so on. 3. Lung cancer: it is necessary to deal with the primary disease as soon as possible, and the tumor should be removed in time in the early stage, which can control the amount of pleural effusion. If the amount of pleural effusion is large, it is recommended to perform thoracentesis or intercostal tube drainage. If the pleural effusion has just been drained and there is water again, it is important to deal with the primary disease as soon as possible and then deal with the pleural effusion. If you do not know the cause, you should seek medical attention and regular treatment under the guidance of a medical professional.