Gastroesophageal reflux can cause chest tightness and difficulty breathing because the esophagus and trachea open together in the pharynx. If gastroesophageal reflux causes gastric juice or stomach contents to reflux into the pharynx and then aspirated into the trachea, it can cause an airway-like bronchial asthma response, resulting in airway spasm. Patients may experience chest tightness and difficulty breathing. Therefore, when treating bronchial asthma, special attention is paid to whether the patient has gastroesophageal reflux disease. If there is a related disease, it should be treated at the same time in order to receive better results, so those who have GERD should pay attention to whether chest tightness and dyspnea are caused by this disease, and should pay enough attention to avoid aggravation of the disease.