GERD refers to a series of symptoms and complications caused by the reflux of stomach contents into the esophagus, airway, throat, nasal cavity, and oral cavity. It can lead to esophagitis to cancer; airway inflammation and spasm; cardiovascular spasm and hypertension; and throat and mouth inflammation and ulcers. These patients may be misdiagnosed as respiratory, ENT, stomatological and cardiovascular diseases for a long time, and always suffer from not being correctly diagnosed and treated. People who drink a lot of alcohol and overeat are prone to GERD. Symptoms mainly include: 1. Gastrointestinal manifestations: acid reflux, heartburn, bloating, belching, regurgitation, mouth bitterness, early satiety after meals, nausea, vomiting, swallowing difficulties, etc., partly accompanied by painful swallowing. 2, respiratory symptoms: may manifest as chronic cough, breathlessness, laryngeal spasm, etc., easily misdiagnosed as bronchitis, emphysema, asthma. It can also be manifested as suffocating awake at night, snoring, and in some cases, even bronchiectasis and pulmonary fibrosis. 3. Chest pain: It occurs behind the sternum or under the raphe, and can be severe stabbing pain when severe, and can spread to the back, chest, shoulder, neck and behind the ear, resembling an angina attack. In some patients, it affects the heart and causes chest tightness, breath-holding, palpitations, premature beats, etc. In severe cases, it may induce angina attack or even heart attack. 4, throat symptoms: manifested as dry throat, itchy throat, sore throat, hoarse voice, foreign body sensation in the throat and difficulty swallowing in the throat, easily misdiagnosed as chronic pharyngitis, long-term stimulation will appear vocal cord polyps, vocal cord white spots and even laryngeal cancer. 5, nasal symptoms: similar to allergic rhinitis attacks, manifested as sneezing, runny nose and nasal congestion, easy to attack in the morning or in contact with hot and cold air. Sometimes it is manifested as sinusitis and rhinogenic headache. 6. Eye and ear symptoms: dry eyes, swollen eyes, itchy eyes, tearing, blurred vision, etc. Tinnitus, itchy ears, hearing loss, recurrent otitis media attacks, etc. may also occur. 7. Oral symptoms: dry mouth, saliva, mouth ulcers, gingivitis, dental caries, abnormal oral sensation such as pain, numbness, etc. 8.Nervous reflex symptoms: manifested as increased or decreased blood pressure, general weakness, weakness, even fainting, pain, numbness, fever or chills in the limbs, easily misdiagnosed as hypertension, cardiovascular disease, cervical and lumbar spine diseases and rheumatism, rheumatoid, etc. 9, other symptoms: unexplained leukopenia, anemia, thrombocytopenia, etc. Unexplained allergy of the body, such as urticaria, allergic purpura, allergic rhinitis, allergic asthma, etc.