Condyloma acuminatum (CA) is a common sexually transmitted disease caused by human papillomavirus (HPV) infection of the genitals, perineum and anus. It is also known as venereal warts, acral warts, anal genital warts and genital warts. It is currently one of the most widespread sexually transmitted diseases. It is a long time ago, as early as the 15th century in Europe before the outbreak of syphilis epidemic, there are descriptions and records of condyloma acuminata, because the clinical performance is spike-like, and the surface is moist, so it is called condyloma acuminata.