The causes of hormone-induced osteoporosis include: 1) inhibiting the absorption of calcium and phosphorus in the small intestine, increasing urinary calcium excretion, causing secondary hyperparathyroidism and promoting bone resorption; 2) reducing pituitary gonadotropin secretion, indirectly causing estrogen and androgen synthesis disorders; 3) inhibiting osteoblast proliferation; 4) causing a decrease in muscle strength and further bone loss; 5) causing bone loss, which can be 12%-20% of bone loss in the first year of medication, and about 3% per year in the subsequent years; the greater the amount of medication, the more bone loss; after 6 months of discontinuing glucocorticoids, part of the bone mass can be restored.