Liver cancer is one of the most common malignant tumors, including different types of hepatocellular liver cancer, cholangiocellular carcinoma, and liver metastatic carcinoma. The pain may involve the right shoulder or right back. When the surface nodes of liver cancer rupture, it may also induce whole abdominal pain. Liver enlargement: The liver of liver cancer patients will be progressively enlarged with hard texture, uneven surface, often with nodules of different sizes, blunt and uneven edges, and often with different degrees of pressure pain. When liver cancer protrudes under the right costal arch or saber process, the epigastrium may show localized elevation or fullness. Jaundice: It usually appears in the late stage of liver cancer, mostly as obstructive jaundice, and a few as hepatocellular jaundice. The former is often caused by tumor compression or invasion of bile ducts, or enlarged extrahepatic lymph nodes compressing bile ducts, while the latter can be caused by extensive infiltration of cancerous tissues in the liver or combined with chronic hepatitis of cirrhosis. Signs of cirrhosis: If the disease develops on the basis of decompensated cirrhosis, it can be manifested as rapidly increasing and difficult to treat peritoneal fluid, multiple leakage of peritoneal fluid, bloody peritoneal fluid caused by liver cancer invading peritoneum or breaking into the peritoneal cavity. It may be combined with severe abdominal infection and coagulation factor deficiency. Systemic manifestations: progressive wasting fever, fever, loss of appetite, weakness, malnutrition, and cachexia, etc. If metastases to the lung bone brain lymph nodes chest cavity, etc., can produce the corresponding symptoms. Some patients have metastatic foci symptoms as the first to be seen. Companion cancer syndrome: a group of syndromes may appear due to metabolic abnormalities of the cancer itself or endocrine metabolism abnormalities of liver cancer patients, such as spontaneous hypoglycemia, erythrocytosis, other rare ones include hypercalcemia, hyperlipidemia and carcinoid syndrome. It should be noted that liver cancer starts insidiously and lacks characteristic symptoms in the early stage, and the occurrence of obvious symptoms is usually in the middle and late stage.