Thyroid nodules are a very common disease, especially in middle-aged women. Thyroid nodules are divided into two categories, benign and malignant, with benign nodules accounting for the majority and malignant nodules for less than 1%. A variety of clinical thyroid disorders, such as thyroid degeneration, inflammation, autoimmunity and neoplasia, can manifest as nodules. Thyroid nodules can be solitary or multiple. Multiple nodules have a higher incidence than solitary nodules, but solitary nodules have a higher incidence of thyroid cancer. There is no need to be nervous when thyroid nodules are found. Seek medical attention to check thyroid function, antibodies and thyroid ultrasound. Among all non-invasive tests, thyroid ultrasound is the most economical and effective method to determine the benignity or malignancy of nodules. If the ultrasound result is suspicious, a fine needle aspiration of the thyroid gland can be done to extract a few tissue cells for pathology to clarify the diagnosis. Even if thyroid cancer is diagnosed, don’t think that the world has come to an end. Most thyroid cancers can be completely cured by surgery and the prognosis is the same as that of benign nodules. Even if there is metastasis, thyroid cancer can survive for a long time after surgery combined with radiotherapy, and among all cancers, thyroid cancer can be considered one of the diseases with the best prognosis.