Sebaceous cyst infection is relatively common in clinical practice. If the infection is mild, local disinfection with iodophor, application of Bactrim ointment or erythromycin ointment, and anti-inflammatory and symptomatic treatment may effectively control the sebaceous cyst infection and the symptoms will gradually disappear. However, for more serious sebaceous cyst infections, surgery can also be considered to cut and drain the infected lesion, and depending on the condition of recovery, a secondary sebaceous cyst can also be completely removed. Patients with infected sebaceous cysts are advised to go to a regular hospital for detailed examination and treatment. When sebaceous cyst infection is usually found, local disinfection, hot compresses or microwave physiotherapy should be taken to control the infection as early as possible, possibly avoiding surgery and using conservative treatment methods to achieve complete cure.