Why is mental illness difficult to treat?

  Psychosis is a functional disorder, and the disease types mainly include: affective psychosis (mania, depression, bipolar disorder, rapid cycling bipolar disorder), schizophrenia, and intractable neuroses (obsessive-compulsive disorder, anxiety disorder, phobias, anorexia nervosa, etc.). The etiology of psychosis is still unclear, and its causative correlates include birth defects, congenital genetics, personality traits, somatic factors, and social and environmental factors stimulation. It is believed that the neurotransmitters in the limbic nuclei of the brain are abnormally secreted, resulting in abnormal levels of neurotransmitters in the body, which leads to disturbances in the patient’s self-regulatory functions, resulting in mental, emotional, and behavioral abnormalities.  Because the cause of psychosis is still unclear, the early treatment of psychosis is mainly based on medication, but as the disease progresses, the effect of medication slowly fails, and about 30%-40% of patients no longer have effective medication and become refractory psychiatric patients. This is also the reason why refractory psychosis arises.