The patient, W, gradually developed mental abnormalities after being stimulated 5 years ago, manifested as follows: sensitive and suspicious, suspecting that his classmates said bad things about him, talking about him behind his back, others’ behavior against him; can smell a strange smell, and can’t tell exactly; exaggerating, thinking he is great, very capable, can do great things, often mentioning Ma Yun and other figures; sometimes impulsively hitting people, destroying things, and having a violent temper; sometimes depressed and Sometimes he was unhappy, and could not be happy; sometimes he talked nonsense, saying that he could communicate with small animals such as puppies and birds, and that the small animals could understand what he said; his mind was confused, and he thought about things, behaved abnormally, went out for no reason, was lazy, and had poor personal hygiene and cleaning ability. At that time, he was seen in the psychology department of a university hospital in Shandong, and was treated with oral olanzapine, and the patient’s symptoms did not improve significantly after taking the medication regularly. In September 2017, he consulted a psychiatric rehabilitation center in Shanghe and was diagnosed with “bipolar disorder and depressive episodes” and was hospitalized for 5 months and given oral Chinese medicine, risperidone and quetiapine as symptomatic treatment. In January 2019, the patient relapsed and was seen again at a psychiatric rehabilitation center in Henan, treated with oral olanzapine, sulpiride, quetiapine, risperidone and other drugs. The patient now has poor sleep, is sensitive and suspicious, suspects that others say bad things about him and talk about him; exaggerates, thinks he is capable; babbles, speaks out of turn; his brain is disorganized, withdrawn, lazy, passive in contact, denies he is ill, has no self-knowledge, impaired social function, cannot study, and cannot take care of himself completely. The patient underwent minimally invasive ablation on March 5, 2019, and was discharged on March 12. All psychiatric symptoms disappeared at the time of discharge, and he knew that he had the disease and went back to take the college entrance examination for revision, and took the college entrance examination in June, and then enrolled in the undergraduate program, which he has now entered. At present, he is emotionally stable and stable, his psychiatric symptoms have disappeared, he eats and sleeps well, he is enthusiastic about studying, he has a good relationship with his classmates and teachers, and he is in a good state of study. Minimally invasive surgery for psychosis is characterized by the elimination of mental symptoms immediately, such as fast recovery of affection, docile temperament, curiosity or curiosity to recover quickly, some children who do not read or study for more than a decade, want to read and study on the second day of surgery, and even decades do not practice the piano, after surgery, once home to practice the piano, etc., good post-operative compliance, obedience, some undesirable problems are very low quickly changed. Why is the recovery so fast after surgery? This is because mental illness is due to abnormalities in the neural circuit, including abnormalities in circuit metabolism, abnormalities in neurotransmitters, etc. Drug therapy is dependent on the drug binding to the receptor, blocking the abnormal receptor to slowly play a therapeutic effect, when the mental illness long-term recurrent attacks, due to neuroexcitatory “toxic” effect, so that the neural circuit structural changes, drug When psychiatric disorders have been recurring for a long time, due to the “toxic” effect of neuroexcitability, the neural circuit is structurally altered, and the drugs may not bind to the receptors or bind less, so the efficacy is poor or even completely ineffective. Some people are concerned about the heavy adverse effects and even think that dementia will occur. At that time, it was a resection, i.e., the prefrontal white matter fibers were cut horizontally, and almost all the prefrontal fibers were cut, so the trauma was very extensive, so about 5% of the cases had dementia, while the modern surgery damage is point-like, unlike the previous damage is piecewise, i.e., the trauma surface is very small, and it is in the deep brain, and the cognitive impact is mainly in the cerebral cortex. Therefore, the adverse effects of treatment are now mild and can be summarized as: predictable, manageable, acceptable, recoverable or disappearable. As in the case of this article, the patient was admitted to university after just over 2 months of postoperative review. We have followed hundreds of patients after at least 1 year to almost 5 years of observation, and about 70% of them went to work after surgery, and even more got married and had children. At present, the current status of psychiatric medication around the world is ineffective, and basically no medication is effective at the advanced stage, so surgery has become the last or even the only choice for psychiatric treatment.