The relationship between male infertility and azoospermia! Shanghai male infertility hospital experts said: today’s society is not 60 generations ago, the society is now fast-paced, high efficiency, also because of this many men because of the work pressure, the burden, so that many men are male infertility entangled, and many men in their own infertility do not know, a lot of men are in the case of marriage for a long time his wife’s stomach did not move to pay attention to the problem, then the male infertility and azoospermia? The problem, then male infertility and azoospermia have a relationship? The relationship between male infertility and azoospermia. Azoospermia can be categorized into two main types. The first type is testicular spermatogenic dysfunction, in which sperm cannot be produced, also known as true azoospermia. The second category is the normal function of testicular spermatogenesis, but the vas deferens is blocked, the sperm can not be discharged from the body, also known as obstructive azoospermia. (1) Hereditary diseases: autosomal or sex chromosome abnormality affects testicular spermatogenesis, such as Klinefelter’s syndrome, etc.; (2) Severe systemic diseases and malnutrition can lead to azoospermia; (3) Congenital testicular abnormality: abnormal development of testis or abnormal testicular position can make spermatogenesis impaired; (4) Endocrine disorders, hyper or hypo pituitary, tumor of pituitary gland, or tumor of kidney, can lead to azoospermia; (5) Endocrine disorders, hyper or hypo pituitary, or tumor of pituitary gland. (4) Endocrine diseases, pituitary hyperfunction or hypopituitarism, pituitary tumor, hyperfunction or hypopituitarism, hyperthyroidism or hypothyroidism can affect spermatogenesis and cause azoospermia; (5) Testicular lesions: such as testicular trauma, inflammation, torsion, and testicular vascular pathology; (6) Radiation damage and drugs, especially cytotoxic drugs and other factors, so that spermatogenesis cells in testes are damaged, which can lead to azoospermia in severe cases. Obstructive azoospermia: the patients have normal secondary sexual characteristics, libido, sexual function, normal testicular development and spermatogenesis, but no sperms are discharged due to the obstruction of the vas deferens. The causes include: (1) congenital malformations, such as ectopic head of epididymis, atresia of epididymal ducts, absence of vas deferens or non-development of vas deferens; (2) epididymal ducts are blocked due to the compression of cysts in the epididymis; (3) infections, gonococcus, tuberculosis and some other bacterial infections can cause obstruction of the epididymis and the vas deferens; and (4) injuries can cause the obstruction of the vas deferens.