Medulloblastoma is a common intracranial tumor in children. Tumors with the word “mother” are generally very malignant, and the younger the child, the more malignant it is. Who would want to give a cute baby a needle and infusion, not to mention an operation, and knowing that the prognosis is not good for malignant tumors. After spending a long time in the children’s ward, we don’t have any feeling about having a boy or a girl, as long as we have a healthy baby. The two major killers of brain tumors in children are medulloblastoma and brain stem glioma, and research on medulloblastoma is still on the way. Medulloblastoma originates from the cerebellar earthworm, and because of its rapid growth, it can easily cause obstructive hydrocephalus. The child will show nausea, vomiting, vision loss, etc. Some parents will consult gastroenterology for treatment, while some will consult ophthalmology, and a fundus check will reveal edema of the optic papilla, and a cranial MRI will reveal intracranial lesions. The first ward of neurosurgery in Tiantan Hospital has accumulated a lot of experience in the treatment of medulloblastoma, for children with hydrocephalus, ventriculoperitoneal shunt is performed first to relieve the intracranial pressure before surgery to remove the tumor, so that the risk of surgery is greatly reduced; for those without hydrocephalus, of course, the tumor is removed directly, but such patients are still relatively few. Without comprehensive treatment, recurrence of malignant tumor is inevitable. Many of the children have already passed away and their families are not cooperative with the follow-up, who would like to reveal their scars. With the development of technology, different subtypes of medulloblastoma have emerged, including: classic, pro-fibroblastic, medulloblastoma with extensive nodules, mesenchymal and large cell types, of which classic and pro-fibroblastic have a better prognosis. In addition to the differences in pathological subtypes there are molecular markers that characterize them. The efforts of neuro-oncologists allow us to tell the family what the prognosis of the child will probably be, in time is approximate. One of my fellow countrymen discovered his child’s medulloblastoma ten years ago, and ten years later, he comes back every year for a review, which is one of the better prognosis categories of medulloblastoma, except that it was not staged ten years ago. It is our common expectation that there will be drugs for the treatment of medulloblastoma in the next decade.