(Disclaimer: This article is for scientific purposes only, in order to protect the patient’s privacy, the relevant information in the following content has been processed) Abstract: This is a 78-year-old male patient, who came to the clinic mainly because of unconsciousness with fever for 3 days. After the consultation, urgent examination of CT suggested left temporoparietal lobe occupation and abscess possibility, and after perfecting cranial MR, brain abscess was diagnosed, after anti-infective treatment, further brain abscess puncture tube drainage was performed, and pathological examination suggested a large number of neutrophils in the pus, which clarified the diagnosis of brain abscess, and anti-infective treatment was continued. After treatment, the patient’s intracranial abscess was cured and recovered well. Basic information] Male, 78 years old [Type of disease] Brain abscess [Hospital] Qingdao Hospital of Traditional Chinese Medicine [Time of consultation] January 2021 [Treatment plan] Surgical treatment (puncture tube drainage) + drug treatment (injection of vancomycin hydrochloride + injection of ceftriaxone sodium) [Treatment cycle] Hospitalization for 45 days [Treatment effect] Brain abscess cured, recovery is good I. Initial interview The patient came to us for 3 days with unclear consciousness and fever. The patient came to the clinic with unclear consciousness and fever for 3 days. Three days before the onset of the patient’s illness, he had a sudden onset of impaired consciousness without any obvious cause. His family found that he had slurred speech, decreased memory and disorientation, accompanied by a low-grade fever, so he came to our hospital for consultation. Physical examination: drowsiness, aphasia, decreased orientation, comprehension, etc. Bilateral pupils were equal in size and round, with a diameter of about 3 mm, sensitive to light, the right nasolabial sulcus was slightly shallow, and the neck was mildly resistant. Left limb voluntary movement, muscle strength muscle tone is normal, left limb muscle strength grade 5, left Babinski sign is positive. The left Babinski’s sign was positive. There were a few wet rales at the bottom of both lungs, so he was admitted to the Department of Neurology. After admission, CT showed that the left temporoparietal lobe was occupied and an abscess was possible. The patient developed high fever in the department of neurology and was transferred to the department of neurosurgery. Communication with the family, check the cranial MR suggests: brain abscess. Blood routine, PCT, all suggest that the patient’s systemic infection symptoms are heavy, proposed surgical treatment, the family accepted the program, first given injection ceftriaxone sodium anti-infection treatment, the patient’s lung infection sputum culture for Staphylococcus aureus infection, a common causative organism of brain abscess, so it was changed to injectable vancomycin hydrochloride anti-infection. After the patient’s condition improved, the patient had surgical conditions, emergency brain abscess puncture tube drainage, pathological examination showed a large number of neutrophils in the puncture fluid, clear brain abscess, and continue to use injection vancomycin hydrochloride anti-infection. The patient’s temperature returned to normal after surgical treatment and medication, and the infection indexes such as blood routine, calcitoninogen and endotoxin apparently returned to normal gradually. After 45 days of hospitalization, the patient’s mentality gradually became clear, speech improved significantly, slightly slower speech, memory and comprehension recovered, neck resistance disappeared, left limb muscle strength returned to normal, and CT and MR indicated that the brain abscess was cured, and the patient and his family were satisfied with the treatment effect and were allowed to be discharged from the hospital. Precautions Through treatment, the patient’s condition was cured, and I was also happy for the patient. After the patient was discharged from the hospital, he should also pay attention to his own living habits, and a good lifestyle will help his condition recover. First of all, after going home, you should pay attention to rest, avoid exertion, avoid heavy physical labor, after recovery, you can gradually begin to exercise; diet is based on high protein, high vitamin, high fiber food, low-salt, low-fat diet, avoid spicy and stimulating food; pay attention to monitoring the changes in body temperature; 1 week after the rechecking of the blood routine, PCT, changes in liver and kidney function; 2 weeks after the rechecking of craniocerebral CT or craniofacial MR; if there is a headache, dizziness, If there is headache, dizziness, nausea, vomiting, impaired consciousness, fever, neck discomfort, follow up and review in time. Brain abscess is a serious intracranial infectious disease. In recent years, with the application of antibiotics, the number of patients with brain abscess has gradually decreased, but if it occurs, it will seriously jeopardize the health of patients and even threaten their lives, so it is necessary to actively cooperate with the treatment. The treatment of brain abscess mainly includes appropriate antibiotic anti-infection and surgical treatment. Patients with chronic inflammation of the ear and nose should be treated thoroughly as soon as possible, and if they feel unwell, they should consult a doctor in time.