Acupuncture Treatment Acupuncture is now more popular internationally for the treatment of PD, which is considered by Chinese medicine practitioners to belong to the category of “tremor” and “internal wind”. Clinically, Chinese medicine classifies PD into 4 types: phlegm-heat and wind movement, Qi stagnation and blood stasis, Qi and blood deficiency, and liver and kidney yin deficiency. Acupuncture treatment has been developed for a long time and its efficacy is now generally recognized, but the mechanism of acupuncture treatment for PD is not yet fully understood. In recent years, the following hypotheses about the efficacy of acupuncture have been developed: Increase in dopamine neurons The pathology of PD is characterized by chronic degeneration of dopamine neurons in the striatum of the substantia nigra, with environmental toxins and genetic susceptibility as suspected causes. Tyrosine hydroxylase (TH) is the rate-limiting enzyme for dopaminergic neuron formation and can be used as a marker to measure dopamine neuron regeneration. A recent animal study showed that after continuous acupuncture treatment of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) PD rats, TH was significantly increased in the basal ganglia region, and the secretion of neurotoxins was significantly disturbed as shown by quantitative SPECT scans. Another experiment confirmed that acupuncture treatment promoted the expression of neuroprotective genes and inhibited the expression of apoptotic genes in the thalamus of PD rats, protecting cells in the MPTP environment. Similar studies have reported that acupuncture treatment increases the expression of neuroprotective genes such as DUSP4, UCP2, etc., which can reduce the level of intracellular oxidative stress and remodel neuronal cells. In addition to the analysis of fine intracellular pathways, additional basic research and clinical observations have shown that increases in brain-derived neurotrophic factor (BDNF) and glial-derived nerve growth factor (GDNF) can be monitored after acupuncture treatment. A recent study showed that high expression of dopamine transporters was monitored in damaged parts of the brain after treatment of 6-hydroxydopamine (6-OHDA) PD rats with high-frequency electroacupuncture (EA), suggesting that EA may be mediated by stimulation of presynaptic and postsynaptic dopamine transporters. A systematic review of recent years of classical acupuncture practice has shown that acupuncture is an effective and safe alternative treatment for PD patients who have failed traditional pharmacological treatment. However, the authors also noted that the clinical practices selected were from different countries, and there were no uniform standards for the selection of acupuncture sites, the timing of acupuncture sessions, and the evaluation of treatment effects, which is a dilemma for the further promotion of acupuncture treatment worldwide. At present, the commonly used acupuncture points in clinical practice are Baihui and Dazhi points to supplement the deficiency of liver and kidney and to raise the deficiency of qi and blood, which are often combined with traditional Chinese medicine and acupuncture to supplement the body with different TCM PD classifications in order to slow down the progression of the patient’s disease.