History abstract Ma Moumou, male, 75 years old, 2011.7 A hospital physical examination CT multi-stage enhancement: nodule in the left inner lobe of the liver, considering hepatocellular carcinoma. He had a history of chronic hepatitis B and lumbar spine trauma. The first TACE was performed on July 8, 2011, and post-interventional CT showed incomplete iodine oil deposition in the lesion (Figure 1). RFA or MW treatment was recommended. However, the patient was of advanced age with hypertension, coronary artery disease and diabetes mellitus. The anesthesiology department evaluated the high risk of anesthesia and did not recommend general anesthesia. On 2011.8.2, percutaneous hepatic perforation tumor injection (DDP + iodized oil) was performed (Figure 2). 2011.9.23 DSA imaging suggested that the original lesion was still stained, and the CT lesion was still active after TACE, so radioactive 125I particle implantation was performed on 2011.12.15 (Figure 3). 2012.5.17 review of the right lobe of the liver showed that the new lesion was possible (Figure 4). DSA showed nodular staining foci in the right lobe of the liver, and the left inner lobe of the liver was unclear (Figure 5). Application of CTA (Figures 6-7) and CTAP techniques of DSA confirmed that the lesion in the left inner lobe of the liver was still active. The patient could not achieve radical treatment with current therapies, and the elderly patient, hypertension, and diabetes mellitus could not tolerate radiofrequency ablation or microwave therapy under general anesthesia. Finally, argon helium knife was chosen to perform cryoablation of iodine oil labeled spots after TACE. Zheng Lin, Department of Radiology and Interventional Medicine, Henan Cancer Hospital, Henan Province, China Adverse reactions and complications TACE and puncture drug injection did not have complications such as cholangioma, liver abscess, etc., and argon-helium knife ablation did not have complications such as hemorrhage, abscess, pneumoperitoneum, and infection. Treatment effect and follow-up 2012.7 review CT efficacy reached CR (cure). Commentary1, TACE combined with non-vascular treatment.TACE is the first choice of non-surgical treatment for primary liver cancer, tumor puncture injection is an effective complementary treatment to TACE, and 125I particle implantation further improves the efficacy of non-resectable liver cancer.2, Xper CT in TACE.Xper CT imaging improves the detection rate of hepatocellular carcinoma, and it can accurately locate the blood supply of the tumor and guide the treatment. embolization therapy, and can evaluate iodine oil deposition after TACE.3, Radical treatment by TACE combined with argon helium knife.The embolic labeling effect of TACE, and TACE combined with argon helium knife effectively improve the prognosis of patients. Figure 1 Figure 2 Figure 3, 125 iodine particle implantation Figure 4 Recurrent foci in the right lobe of the liver (white intensified spots in the liver) Figure 5 Right lobe of the liver lesion contrast shows that the left lobe of the liver where protoiodine particles were implanted + puncture and injection is not sure whether there is activity or not Figure 6 Figure 7