Uric acid 500μmol/L can lead to kidney stones, but it does not mean that kidney stones will definitely occur with uric acid 500μmol/L, the specific situation varies from person to person. In addition to the close relationship with the kidney lesion itself, kidney stones are also closely related to diet and other factors. 1, kidney lesions: If the kidney has basic lesions, such as cysts, or viral or bacterial infections, the presence of basic lesions will lead to an increase in the local urate concentration, and once it exceeds the saturation solubility of uric acid, urate crystals will be formed, and with the continuous increase of urate crystals, thus forming Uric acid kidney stones; 2, dietary factors: if you eat too much food containing protein, it will lead to acidic urine, uric acid is more likely to form crystals, resulting in uric acid kidney stones. However, if you eat more vegetables, fruits, cereals and other foods, urine is neutral or alkaline, even if uric acid is elevated, it will not necessarily produce kidney stones. In addition, the production of kidney stones is also affected by the amount of water consumed daily. If you drink more water daily, your urine is diluted and the concentration of uric acid is not high, which usually does not lead to the formation of uric acid kidney stones. However, if you drink less water, the concentration of uric acid in the urine is higher, which will easily induce kidney stones. Therefore, it is recommended that patients with 500 μmol/L uric acid should maintain a reasonable diet structure and drink an appropriate amount of water daily to prevent the occurrence of kidney stones.