Chronic kidney disease stage V is the uremic phase, failure to treat the wrong treatment, at any time life-threatening, but the survival period of several decades. Chronic kidney disease stage V is the uremic phase, which is the late stage of chronic renal failure, the glomerular filtration rate of patients in this stage is <10ml/min, blood creatinine >707μmol/l. The main clinical manifestations are back pain, weakness, edema, hypertension, 24-hour urine volume gradually decreases, all systems of the body can be involved, and the corresponding symptoms appear. Patients need to undergo renal replacement therapy, and the average survival period is 10-15 years, which is related to the patient’s own condition, the presence of complications, disease control and compliance. In general, patients can survive for decades after normal dialysis; if they have poor dietary control or more complications, they may only survive for 5-10 years. It is recommended that patients should pay attention to diet control, control blood pressure and blood sugar, choose a high-quality low-protein, low-phosphorus, low-potassium diet, and supplement folic acid and water-soluble vitamins at the same time as treatment.