Ureaplasma urealyticum is a mycoplasma infection that does not usually heal on its own and requires aggressive treatment. Patients infected with Ureaplasma urealyticum will experience symptoms such as frequent urination, urgency, painful urination, burning in the urethra, purulent discharge from the urethra, and hematuria in the naked eye. It is closely related to human genitourinary tract infections and is mainly transmitted through sexual intercourse and belongs to the category of sexually transmitted diseases. Once this infection occurs, drugs should not be used randomly to avoid harm to the body. Treatment should be done with drug sensitivity test, and symptomatic treatment after selecting more sensitive drugs, common drugs are azithromycin, doxycycline, etc. In addition, couples should be treated at the same time, and after about 15 days of treatment with medication, the medication should be stopped for a week and then rechecked. Couples with the disease should pay attention to washing underwear separately and not to use the bidet. Underwear should be frequently disinfected by exposure to the sun in order to kill pathogens. During the treatment period, sexual intercourse is forbidden, and the diet should be light, with less spicy and other stimulating foods.