The interrelationship between prostatitis, prostate enlargement and prostate cancer has been a common concern for patients with prostatitis. Although all three diseases are common, some clinical symptoms are similar, and all occur in the prostate, research on prostate enlargement and prostate cancer has been extensive in recent years, but research on prostatitis is relatively scarce, and research on the interrelationship between prostatitis and the other two prostate diseases is even poorer. It is a known fact that prostatitis commonly occurs in young adult men, while prostate enlargement and prostate cancer often occur in older men over the age of 50. Therefore, a question often asked by patients is whether prostatitis suffered at a young age can lead to prostate enlargement and prostate cancer in later life. According to studies, 98%-100% of prostate glands surgically removed for prostate enlargement have evidence of histological changes of prostatitis; 50% of prostate tissue biopsies from prostate cancer patients have evidence of histological changes of prostatitis. Theoretically, prostatic hyperplasia leading to lower urinary tract obstruction, decreased urethral mucosal resistance, urinary reflux, and concomitant urinary stones make prostatic hyperplasia prone to complications of prostatitis, but few relevant studies have been reported at home and abroad. There is no definite conclusion on the interrelationship of these three diseases, and on the surface there is no direct and inevitable connection between them, but only after an in-depth and comprehensive study can the question be better answered.