In order to get pregnant, Mr. and Mrs. Wang are exercising and supplementing their nutrition, and even ovulation is well calculated, but more than a year has passed, but his wife’s belly is still not moving. The couple had to go to the hospital for a checkup, but they didn’t expect to come up with a “strange” diagnosis: semen is not liquefied resulting in infertility. What is seminal fluid non-liquefaction? There are many people who are as confused as Mr. and Mrs. Wang. In order to facilitate the stay in the female vagina, the freshly ejaculated semen is initially solidified, at which time the sperm is inactive, and then the solidified semen will be liquefied in a short time before the sperm starts to move. Under normal circumstances, this process will not take more than one hour. If it exceeds, the semen is not liquefied and will lead to a long period of restricted sperm activity resulting in infertility. The reason why the normal state of semen is first coagulated and then liquefied is because of the presence of protein coagulase and proteolytic enzymes in semen. The former is mainly from the seminal vesicles and the latter is mainly from the prostate. Under normal circumstances, the two enzymes play a coordinated role and work together to complete the physiological change process of semen. If there is a problem with the prostate or/and the seminal vesicles, the original equilibrium will be upset, resulting in abnormal semen liquefaction. The most common cause is prostatitis, which causes a decrease in the secretion of lysozyme, resulting in non-liquefaction. In addition, varicose veins and other diseases can cause endocrine dysfunction of the testes, reducing the secretion of testosterone and leading to a decrease in the secretion function of the accessory sex glands (including the prostate and seminal vesicle glands), which can also lead to the phenomenon of semen not liquefying, thus affecting the vitality of sperm. However, some clinical patients with prostatitis do not have liquefaction abnormalities. It may be that these patients have combined seminal vesiculitis at the same time, i.e. they also have reduced secretion activity of the seminal gland, which brings the coagulation and liquefaction to a new equilibrium state. Combined Chinese and Western medicine treatment is effective: For patients with semen that is not liquefied, we first give them routine laboratory tests of prostate fluid. In general, the key to treating semen non-liquefaction is to see if prostate function can be restored. At present, the clinical treatment mostly applies antibiotics and taking high doses of vitamin C. The actual fact that there is a fat-soluble fiber envelope around the prostate gland, antibiotics generally use fat-soluble drugs, so that the prostate gland can gather a high concentration of drugs to play a bactericidal role. Vitamin C is a bioactive reducing agent that plays an important role in fighting oxygen free radicals in semen and improving the physicochemical state of semen. In addition, patients with prostatitis often have a deficiency of the trace element zinc in their semen, and supplementation of such trace elements can help restore prostate function. For example, malt and hawthorn can lower the pH of semen and prostate fluid and enhance the activity of semen liquefaction enzymes; malt also contains amylase, which accelerates the liquefaction of semen; salvia has the effect of dilating blood vessels and promoting the smooth drainage of prostate gland ducts, and improves the reproductive internal environmental conditions for sperm production, maturation and survival through the overall regulatory mechanism, so that the quality of semen is generally improved and conducive to conception. It is advisable to have a semen test before marriage: although treatment can improve the condition of low sperm vitality, it is still difficult to cure it completely. It is best for men to do a semen test before they get married and check the prostate routine items to achieve early detection and early treatment to avoid too much disagreement or even emotional breakdown after marriage due to infertility. The male should be more self-love. There is an STD after prostatitis that stems from a history of unclean sexual intercourse, mostly belonging to chlamydia, mycoplasma infection. If the husband suffers from this prostatitis, it may be transmitted to the wife during intercourse, causing infection in the reproductive tract of the other party, thus causing tubal incompetence and leading to infertility.