Tuberculous pleural effusion is a manifestation of tuberculous exudative pleurisy, which is the most common cause of infectious diseases of the pleura and is second only to lymphatic tuberculosis in terms of incidence among extrapulmonary tuberculosis. Tuberculous pleural effusion can be divided into inflammatory exudative phase, segregation formation phase, dense segregation phase, abscess pleural phase, and late abscess pleural phase. Why does tuberculous pleural effusion tend to form diaphragm and parcel? This is because in patients with tuberculous pleural effusion, the pleural water contains a large amount of fibrin fibrinogen and their degradation products. Fibrinogen and its decomposition products are one of the main substances of coagulation and have coagulation effect, which makes the pleural fluid viscous and easy to produce protein clots, and if the treatment is not timely or improper, the fluid will be separated and wrapped in small cavities in multiple rooms, thus affecting the absorption of pleural fluid. The formation of a tuberculous pleural effusion with a divided diaphragm causes certain difficulties in the drainage of the pleural effusion; the formation of a tuberculous package makes it difficult for drugs to reach directly and makes it easy for the effusion to recur. In layman’s terms, the formation of an encapsulation is like having a small house, and the organism will not let the small house be empty, and it will repeatedly produce pleural fluid. Tuberculous pleurisy cannot be controlled for a long time, it will develop further, and even pleural adhesions and hypertrophy will lead to failure of clinical pleural puncture and drainage, prolonging the course of the patient’s disease, making treatment difficult and eventually developing into an abscess chest, forming a large number of dense separations, thickening the package, reducing the concentration of local drugs, and eventually developing into an abscess chest, which can only be treated by fibrous debridement, with much surgical bleeding and trauma. It brings pain to patients. So once tuberculous pleural effusion is found, the pleural fluid must be pumped out as soon as possible, and with the anti-tuberculosis systemic treatment, the chest cavity forms a divided diaphragm, parcel, abscess chest, etc., which affects further treatment. And no matter to which period the disease has developed, treatment should be based on the characteristics of that period to effectively control the disease.