On the morning of May 22, Shanghai Zhabei District Central Hospital successfully performed ultrasound-guided microwave ablation of a thyroid nodule for a male patient from Taiwan. The immediate postoperative ultrasonography showed that the patient’s huge nodule on the right side of the thyroid had been ablated by more than 50%. Although the patient was 74 years old, he had a high degree of trust in Director Zhang and was calm during the surgery, controlling his breathing smoothly. It is understood that this is the first case of ultrasound-guided microwave ablation of thyroid nodules for Taiwanese patients in Zhabei District Central Hospital. Mr. Chen, 74 years old this year, unintentionally found a lump in his neck. After examination, he found that there were several nodules in his thyroid gland, including a huge nodule on the right side of the thyroid gland, measuring about 67×46mm. For various reasons, Mr. Chen did not want to undergo surgical treatment, so he sought medical help but was unsuccessful and delayed the surgery. With a dark mood, he searched and browsed on the Internet, and inadvertently, the exchange between Professor Zhang Jiangyan of the Ultrasound Department of Shanghai Long March Hospital and the patient caught the attention of Mr. Chen’s family. At that time, I was a little excited and felt that my thyroid gland could be preserved. Through communication with Prof. Zhang and ultrasound examination, Prof. Zhang gave a treatment plan recommending surgical removal because of Mr. Chen’s advanced age, huge thyroid nodules and the richness of blood vessels in the nodules. However, Mr. Chen firmly refused the traditional surgical option and strongly requested microwave ablation of thyroid nodules under ultrasound guidance. During the operation, the patient, who was under local anesthesia, was awake all the time and communicated with Prof. Zhang from time to time. Under ultrasound dynamic monitoring, Prof. Zhang inserted the water-cooled microwave needle into the giant right thyroid nodule and caused coagulative necrosis of the lesion tissue through the action of microwave field to achieve in situ inactivation and cure. The next day before discharge from the hospital, Mr. Chen and his family went to the Department of Physical Medicine to say goodbye to Director Fang, who was on duty, and expressed their heartfelt gratitude: “Thank you very much, Professor Zhang, Director Fang and other medical team. It is your excellent medical skills and continuous innovation in the medical field that allow us to have a better treatment method. Although we had read all your articles and online exchanges before coming to your hospital, and had some understanding of the thermal ablation technique for thyroid nodules, I still had doubts about whether my bilateral nodules, which are large and multiple, could be resolved successfully. At the end of the surgery yesterday, I tried to say “Thank you, Professor Zhang”, and when I heard my own voice, my heart dropped completely! The haze in my heart finally lifted, and I smiled happily for the first time since I had been to the doctor. According to the pre-operative treatment plan, another microwave ablation is needed, and the treatment is not yet completely finished, but we have been deeply touched by the high medical ethics and medical skills of Prof. Zhang and the medical team of Director Fang. They are very kind and humorous, with excellent medical skills and modesty. We would like to express our deep gratitude to the doctors and nurses of the endocrinology and surgical anesthesia departments who took good care of me during my hospitalization. Fang Chao, director of the hospital’s physical medicine department, introduced that thyroid nodules are the most common disease of the thyroid gland. At present, the traditional treatment is surgical removal, but the surgery itself is risky, with more complications and post-operative scars affecting the aesthetics. To be honest, although Mr. Chen chose microwave ablation before the operation, he was still in an apprehensive mood because none of the major hospitals in Taiwan had implemented this new technology. After careful explanation by Prof. Zhang and us, Mr. Chen had a more in-depth understanding of this procedure: the ultrasound-guided microwave ablation treatment carried out by Shanghai Changzheng Hospital Branch Shanghai Zhabei District Central Hospital is highly safe, less risky, minimally invasive, and The procedure can be easily achieved with little pain. With the cooperation of many parties, the first case of microwave ablation of thyroid nodules was successfully carried out in our hospital on August 22, last year. As of May 20 this year, more than 70 cases of microwave ablation for benign and malignant thyroid nodules, parathyroid hyperplasia, hepatic hemangioma, kidney cancer and other diseases were successfully performed under local anesthesia, and the whole procedure took only 10-30 minutes, bringing good news to patients.