After Jiang Tingyin, a scholar from our hospital who went to the United States, returned to China in 1987, he was the first one to use 32P isotope in the treatment of postoperative gliomas in China, and then invented the balloon intracellular radiotherapy device (i.e., collectively known as the balloon method in the academic world); we further improved and expanded the application of the clinical promotion, and achieved remarkable clinical results, and many higher-grade gliomas have been clinically cured with 6 years of no recurrence, thus the balloon 32P isotope intracellular radiotherapy has been regarded as the “nemesis of postoperative gliomas” in the Health News. Therefore, the balloon method of 32P isotope interstitial radiotherapy for postoperative gliomas was once regarded as “the nemesis of gliomas” by Health News. With the continuous summing up of experience, we have applied hyperbaric oxygen’s sensitization and treatment of cerebral edema to internal radiotherapy, which further improved the efficacy and quality of survival, and then adopted 125I with a long therapeutic radius of validity as well as improved the balloon to a multi-footballoon and other measures, which reduced the recurrence rate of the tumors. Recently, we have applied microfluorescence technology, functional MRI, and electrophysiological monitoring to surgery, which has increased the tumor resection rate and preserved brain function to the maximum extent. We have treated more than 3,000 cases of patients from all over the country, and have gained rich experience and obvious treatment effects, won five provincial and municipal awards, participated in many national academic lectures and experience exchanges, and organized national technical training and academic forum meetings. We have a specialized glioma treatment center and treatment team, and we are a public Grade 3A general hospital. The treatment of glioma emphasizes individualized comprehensive treatment, and there are 2 keys, surgical resection is one of them, and the other key is to adopt continuous and effective treatment after surgery, and the balloon method of isotope internal radiotherapy is a kind of continuous and effective treatment. The balloon method only uses a syringe to puncture the subcutaneous injection pump to regularly change to new isotopes such as 32P and 125I, etc. The balloon method uses a syringe to puncture the subcutaneous injection pump to periodically change to new isotopes. The balloon method of internal radiotherapy device method is simple to operate, low cost, no need for hospitalization, and can be a multi-course treatment without obvious side effects, is currently the most scientific and effective radiotherapy measures, but also our invention of the treatment method. This method can kill the tumor cells once they enter the proliferation and division stage, and can be applied repeatedly for multiple courses of treatment, solving the problem that external radiotherapy can only be applied once in a lifetime and other internal radiotherapy requires stereotactic surgery to implant the radiotherapy source, which has remarkable therapeutic effect, low recurrence rate, high quality of patient’s survival, and effectively prevents the nausea and vomiting, as well as the radioactive brain damage, hematopoietic function decline and other side effects. At the same time, combined chemotherapy can really synchronize radiotherapy and chemotherapy and play a synergistic effect, improve the tolerance of patients’ comprehensive treatment and improve the therapeutic effect. Hyperbaric oxygen therapy can not only increase the sensitivity of radiotherapy but also treat various brain injuries. Therefore, we have many patients who have been through surgery, radiotherapy and chemotherapy in Beijing and Shanghai with poor results or relapse and come to our hospital to adopt our unique personalized comprehensive treatment and get unexpected results. Their testimonials are our reputation.