I. High incidence of osteoporotic fractures With the rapid aging of the population, osteoporosis and the resulting fractures have become a serious medical challenge. Osteoporosis is a systemic, metabolic disease of the bone marrow system, which is closely related to age, gender, race and other factors, and is more prevalent in postmenopausal women, and is pathologically characterized by decreased bone mass, destruction of bone microstructure, increased bone fragility, decreased bone strength and susceptibility to fracture. Among these, fracture is the most serious consequence of osteoporosis and is often the first symptom and reason for consultation in patients with osteoporosis. One study reported that in 2006, about 69.44 million people over the age of 50 in China suffered from osteoporosis and about 21.39 million people had low bone mass. Taking hip fracture, the most serious consequence of osteoporotic fracture, as an example, the number of patients and the medical costs required were 690,000 and 6.4 billion yuan, respectively, in 2006; they are expected to reach 1.64 million and 85 billion yuan, respectively, in 2020. An epidemiological survey conducted in Taiwan, China, predicts that the incidence of hip fracture in the population of the region will be 3.7 times higher in 2035 than in 2010. In addition, 22 million women and 5.5 million men in the EU27 suffered from osteoporosis in 2010, and 3.5 million people suffered from fragility fractures, with an associated economic burden of 37 billion euros, of which fracture treatment accounted for 66%, postoperative care for 29% and drug prevention for 5%; the cost is expected to increase by 25% in 2025. The main characteristics and treatment difficulties of osteoporotic fractures are: patients are mostly elderly, often combined with other diseases, prone to complications; most of them are comminuted fractures, the stability of internal fixation treatment is poor, the built-in object is easy to loosen, dislodge, and the bone implant is easy to be absorbed; bone formation and bone scab maturation is delayed, prone to delayed fracture healing or even non-healing; bed-braking period will occur rapidly The risk of re-fracture increases significantly due to rapid bone loss during the bed-braking period; the rate of disability and death is high; the incidence of re-fracture is high, and the rate of re-fracture in hip fracture patients is 20% within one year. Third, prevention is more important than treatment Prevention of osteoporosis and osteoporotic fracture is more important than treatment. The basis of osteoporotic fracture is osteoporosis, and etiological treatment must be emphasized. Those who do not yet have osteoporosis but have risk factors for osteoporosis should do a good job of primary prevention of osteoporosis, and the aim of prevention and treatment is to prevent or delay the development of osteoporosis into osteopenia and to avoid the first fracture. In contrast, in patients with a bone mineral density (T) ≤2.5 or who have already had a fragility fracture, the ultimate goal of prevention and treatment is to avoid a fracture or another fracture. It should be emphasized that prevention should begin in infancy and continue throughout life, and adolescents, pregnant women, perimenopausal women, the elderly, and people with osteoporosis are the key populations for prevention, and preventive measures should be implemented at the grassroots level, starting with health education.