Thyroid nodules are generally referred to as nodular goiters, which are due to repeated or sustained hyperplasia of the thyroid gland under the long-term stimulation of increased thyroid stimulating hormones, resulting in uneven enlargement and nodule-like changes in the thyroid gland. Smaller thyroid nodules do not have any clinical symptoms, while those with symptoms have the following clinical manifestations: 1. The thyroid gland is enlarged, initially diffusely and symmetrically, then single or multiple nodules of varying sizes and textures appear, asymmetrically. 2. Cystic degeneration, necrosis, hemorrhage, fibrosis or calcification may occur in thyroid nodules, and intracapsular hemorrhage or cystic degeneration may rapidly increase in size within a short period of time, resulting in pain. 3. Nodules grow slowly and can move up and down with swallowing. With the enlargement of the gland and the increase of nodules, compression symptoms may appear: tracheal compression, there will be a sense of blockage, poor breathing, and even breathing difficulties, the trachea can be narrowed, bent and displaced or softened; esophageal compression, the huge goiter can be extended between the trachea and esophagus, causing its swallowing difficulties; laryngeal nerve compression, will lead to hoarseness; cervical sympathetic nerve compression, there can be Horner syndrome (sunken eyes, pupils become smaller In the case of cervical sympathetic nerve compression, Horner’s syndrome (sunken eyes, small pupils, drooping eyelids) may occur; in the case of superior vena cava compression, superior vena cava syndrome (unilateral swelling of the face, neck or upper limbs) may occur. In nodular goiter, ultrasound often indicates multiple hypodense lesions in the thyroid gland with heterogeneous changes such as cystic, solid, and mixed. Ultrasound is currently the better imaging diagnostic method for thyroid nodules.