Irbesartan and Chlorosartan Potassium cannot be evaluated to see which one has less side effects, and different patients may experience different side effects. Irbesartan and Chlorosartan Potassium belong to the same class of drugs, both have similar mechanism of action, both through the inhibition of angiotensin II receptors in the body to play the role of antihypertensive effect, both can be used for the treatment of high blood pressure; the process of lowering blood pressure will have some side effects, but due to the different response of different patients to the drug, it is not possible to assess the magnitude of the adverse effects of the drug, and there are differences between the different patients. Irbesartan and chlorosartan adverse reactions are also similar, dizziness, nausea, nasal congestion, cough, edema, creatinine elevation and other side effects may occur during drug administration, allergy to drug components, severe renal insufficiency, lactation and pregnancy women are prohibited. Clinical oral Irbesartan and chlorosartan potassium to lower blood pressure, pay attention to the adverse reactions and side effects of the drug, under the guidance of a physician to use the drug.