Gout is a disorder of purine metabolism, caused mainly by increased levels of uric acid in the blood. The human body is like a machine in constant motion, constantly metabolizing to provide energy for the normal function of tissues and organs, and also constantly producing metabolic waste. It is like a car, which constantly uses gasoline to generate energy to propel itself forward, but also produces exhaust gas and water. Uric acid is a metabolic waste product of purines. If for some reason the production of uric acid increases or its excretion decreases, the concentration of uric acid in the blood increases accordingly, resulting in hyperuricemia. Uric acid is deposited in the form of crystals in various parts of our body, causing a foreign body inflammatory response in these areas, which can lead to disease. Most commonly, it is deposited in tissues and organs such as joints, cartilage and kidneys, so the common symptom of gout is arthritis, followed by gout-induced kidney disease. Gouty arthritis is very painful and can lead to joint deformities over time, which is more harmful. 1, how does gout occur Gout can be divided into primary and secondary two. Primary gout has a family history in 25% of cases and is autosomal dominant. The main reason is that some enzymes in the purine metabolism process are abnormal, leading to an increase in uric acid production. Secondary gout is caused by a decrease in kidney function due to various kidney diseases, resulting in a decrease in uric acid excretion from the body. Tips: Chromosomes are thread-like or rod-like objects composed of deoxyribonucleic acid, protein and a small amount of ribonucleic acid, which are the carriers of the main genetic material of living organisms. There are 23 pairs of normal human chromosomes, 22 of which are autosomes. There is also one pair of sex chromosomes, which determine whether a person is male or female. For each child, half of the chromosomes are from the father and half are from the mother. If the autosomes of either the father or mother have disease-causing genes on them, and if they are passed on to the child, the disease develops, it is called autosomal dominant inheritance. 2, what are the symptoms of gout 95% of gout occurs in middle-aged men, women rarely develop, and the symptoms are also lighter than men. However, the incidence of gout in women can increase after menopause. The most important symptom of gout is arthritis, followed by gouty nephropathy. It can also involve other organs and cause corresponding diseases. Tip: Estrogen promotes uric acid excretion and has an inhibiting effect on arthritis attacks. Women’s bodies contain more estrogen, so the incidence of gout in women is small. However, after menopause, the level of estrogen in women’s bodies decreases, which leads to an increased incidence of gout in postmenopausal women. Although men also have estrogen in their bodies, the amount is very small compared to women, so most gout occurs in men. In addition, animal offal and seafood contain more purines, so men have a greater chance of eating these foods. This is compounded by the consumption of alcohol, especially beer, which adds fuel to the fire. These reasons also lead to the vulnerability of men to gout. 3, gout treatment The first thing you should do with gout is to rest in bed, local hot compresses can be applied to increase the excretion of uric acid, such as salicylic acid. If it is a gout stone, you can consider surgery to remove it. 4, the prevention of gout Gout can be prevented! Because the attack of gout is often related to diet, cold, overwork, so the prevention of the first to avoid eating food containing high purine, more vegetables and fruits, followed by the best quit alcohol. Drink more water to increase the speed of metabolism. In addition, it is important to avoid overexertion, cold, and a regular lifestyle to prevent the occurrence of gout. Tips: animal offal such as brain, liver, kidney, heart, belly. And dark-colored meat, Western-style thick meat soup, beef vegetarian, chicken essence, etc. Seafood such as sardines, hamachi, herring, tooth scallops, multi-spring fish, scallops, sea cucumbers, scallops, oysters, mussels, seiyu, shrimp, small dried fish, fish skin, fish eggs, etc. Goose meat, wild animals, etc. These foods contain more purines and excessive intake of such foods should be avoided.