The clinical manifestations of diabetic foot are related to five lesions: neuropathy, vascular lesions, lower limb ulcer formation, infection and gangrene. 1, the performance of diabetic foot neuropathy: due to neuropathy, the skin of the affected limb is dry and sweatless, tingling, burning pain, numbness, dullness or loss of sensation, sock-like changes, feet stepping on cotton wool feeling; due to limb malnutrition, muscle atrophy, flexor and extensor muscles lose the normal balance of traction tension, so that the bones sink causing interphalangeal joint bending, the formation of bowed feet, hammer toes, chicken claw toes and other foot deformities. When the patient’s bone joints and surrounding soft tissue strain, continue to walk easy to cause bone joint and ligament damage, causing multiple fractures and ligament rupture, the formation of Charcot’s joint. x-ray examination more bone destruction, some small bone fragments from the periosteum to form dead bone. 2, diabetic foot vasculopathy manifestations: cold feet, fear of cold or heat, numbness, pain, aggravated in the cold season or at night, some patients will appear intermittent claudication, with the aggravation of the disease will also appear dry skin, wax-like changes, poor elasticity, lower skin temperature, pale or cyanotic skin, sweat hair thinning, toenail dry thick, deformation, muscle atrophy. The dorsal foot artery and posterior tibial artery pulsation is weakened or disappeared, vascular murmur can be heard at the narrowing of the blood vessels, and even ulcers and gangrene in the foot. 3, diabetic foot ulcers can be divided into neurological ulcers, ischemic ulcers and mixed ulcers. Neurological ulcers mostly occur on the bottom of the foot or neurological arthropathy, manifesting as normal foot skin temperature, numbness, dryness, inconspicuous pain, and good foot artery pulsation; simple ischemic ulcers are less common, and these patients have reduced foot skin temperature, which can be accompanied by pain at rest, ulcers and gangrene on the edge of the foot, and disappearance of foot artery pulsation; patients with mixed ulcers have both peripheral neuropathy and peripheral vascular disease. Patients with mixed ulcers have both peripheral neuropathy and peripheral vascular disease.