In recent years, many cases of herbal medicine related nephropathy have been reported one after another. This reality makes us realize that it is necessary to correctly understand the renal damage caused by herbal medicines and correct the prejudice that natural drugs are non-toxic or have little toxicity, and also to avoid generalizing and expanding the understanding of the nephrotoxicity of herbal medicines. The following are the herbal medicines or herbal preparations that may cause kidney damage: 1. plant-based herbal medicines: guanmutong, guangfangji, qingmuxiang, tianxian vine, vinca lily, aristolochia, bonesetter, horsetail, zedoary, leigongtang, etc. 2. Animal herbal medicines: such as fish gall, snake gall, zebra, centipede, seahorse, red maiden, etc. 3.Mineral herbs: arsenic-containing herbs (e.g. Xiong Huang, Arsenicum, Arsenicum, Red Alum); mercury-containing herbs (Vermilion, Light Powder, Ascending Mercury); lead-containing herbs (Lead Dan) and Alum, etc. 4.Common Chinese medicines containing aristolochic acid, such as: Gentian diarrhea liver pill, Ganlu disinfectant dan, stone granules, stone gentleness, gynecological division clear pill, coronary heart Suhe pill, Suhe pill, ten fragrant rejuvenation pill, stop coughing and phlegm pills, etc. The above herbal medicines or pills can cause kidney damage if used in large amounts at one time or in small doses for a long time.