1, drugs to improve renal anemia 1 erythropoietin (erythropoietin, recombinant human erythropoietin, EPO, blood profit, Ebio)
1.1 Dosage, dosage: injection, 1500U, 2000U, 3000U, 4000U, 10000U.
1.2 Usage: Initial dose: 50~150U/kg body weight, subcutaneous injection three times a week; maintenance dose adjusted according to erythrocyte pressure or hemoglobin level.
1.3. Pharmacological effects: The main effect of this product is to bind to the surface receptors of erythroid progenitor cells, promote the proliferation and differentiation of erythroid cells, promote the maturation of erythroblasts, increase the number of erythrocytes and hemoglobin content; stabilize the erythrocyte membrane and improve the function of erythrocyte membrane antioxidant enzymes. Elsewhere, this product can also improve platelet function and improve the hemostasis disorder.
1.4 Precautions.
1.4.1 The main adverse reactions are elevated blood pressure, occasionally induced cerebrovascular accidents, seizures. Others such as pruritus, fever, nausea, headache, arthralgia, thrombosis, etc.
1.4.2 Contraindicated in patients with hypertension difficult to control by hemodialysis, certain patients with leukemia, lead poisoning and pregnant women. Contraindicated in patients with hypersensitivity to this product. Use with caution in patients with epilepsy and cerebral thrombosis.
1.4.3 Strictly monitor blood pressure, thrombosis and serum iron level during application.
2.Fonaid (compound ferrous sulfate)
1.1 Dosage: Compound tablet.
1.2 Usage: Initial dose: one tablet per day orally; maintenance dose: one tablet per day for 2~3 days, adjusted according to EPO dosage.
1.3. Pharmacological action: provide hematopoietic raw materials.
1.4 Adverse reactions.
1.4.1 Gastrointestinal discomfort, abdominal pain and diarrhea, etc.; occasionally can cause constipation. It is generally appropriate to take after meals.
1.4.2 The stool may be black and the patient should be informed in advance.
1.5 Precautions.
1.5.1 Avoid tea when taking, and should not be taken with tannin and antacid sodium bicarbonate to prevent the absorption of iron.
1.5.2 Dilute hydrochloric acid and vitamin C can promote the absorption of iron is often used in combination.
1.5.3 Iron and tetracycline drugs can form complexes, which can impede each other’s absorption.
3.Solifet (ferrous succinate)
1.1 Dosage: tablet, 100mg.
1.2 Usage: Initial dose: 0.2, taken orally 3 times a day; maintenance dose 0.1~0.4/day, adjusted according to EPO dosage.
1.3. Pharmacological action: supplementation of hematopoietic material.
1.4 Adverse reactions and precautions: same as ferrous sulfate tablets
V. Treatment of renal bone disease drugs 1A-osteol (osteotriol, rocalciferol, A- D3 pills)
1.1 Dosage and dosage: 0.25mg in gelatinous form.
1.2 Usage: One capsule daily, adjusted with blood calcium.
1.3. Pharmacological action: This product is a vitamin D3 active type preparation, which can promote intestinal absorption of calcium and promote bone formation and normalize blood calcium values.
1.4 Adverse effects: Blood calcium values should be measured regularly to prevent the occurrence of hypercalcemia. Occasional nausea, loss of appetite and skin scratching. Use with caution in pregnant women.
2.Calcium carbonate
1.1 Dosage: 500mg and 600mg tablets.
1.2 Usage: Initial dose: 0.5~1.0/day, taken orally once a day; maintenance dose adjusted with blood calcium.
1.3. Pharmacological effects: calcium supplementation.
1.4 Adverse effects: May cause belching, constipation. It is contraindicated in patients with renal dysfunction, high urinary calcium or blood calcium concentration, and digitalis.
Commonly used proprietary Chinese medicine 1 Cordyceps sinensis (Bai Ling capsule, Jin Shui Bao capsule)
1.1 Form and dosage: Capsule.
1.2 Usage: 3~6 capsules, 3 times a day.
1.3. Pharmacological effects: Cordyceps sinensis is slightly warm, tonifies the lungs and kidneys, and benefits the essence of blood. Artificial culture of its mycelium can extract nucleosides, polysaccharides and other substances, and has a significant inhibitory effect on T lymphocyte E-ring formation and lymphocyte transformation rate.
2 Leigongjiang polysaccharide tablets
1.1 Dosage form and dosage: 10mg tablet.
1.2 Usage: 1~1.5 mg/kg body weight/day in divided doses for six months.
1.3. Pharmacological effects: This product has strong anti-inflammatory and immunosuppressive effects. It can antagonize and resist the release of inflammatory mediators and the degree of experimental inflammation and arthritis response. It can inhibit T-cell function, inhibit delayed-type metaplasia, inhibit the secretion of interleukin-1, and inhibit schistogenic and antigen-stimulated T-cell division and multiplication.
1.4 Adverse effects: It can cause gastrointestinal reactions such as nausea, and may produce bone marrow suppression or gonadal suppression.
3 Huangkui capsule
1.1 Dosage and dosage: 500mg in capsule form.
1.2 Usage: 5 capsules to be taken orally 3 times a day.
1.3. Pharmacological action: Wasabi is sweet and cold in nature, can clear dampness and heat, detoxify and reduce swelling. Its extracted flavonoids can be anti-inflammatory, diuretic and anti-platelet aggregation.
1.4 Adverse reactions: It may appear that the upper abdomen is full and uncomfortable after the drug is used, and it is advisable to take it after meals. Pregnant women should not take it.