The clinical manifestations of hepatocellular carcinoma include the following aspects: pain in the liver area: it is the most common symptom of hepatocellular carcinoma, mostly presenting as continuous distension or dull pain in the right upper abdomen, which is related to the tumor growth and pulling of the liver envelope. When the surface nodes of liver cancer rupture, it may also induce whole abdominal pain. Liver enlargement: The liver of liver cancer patients will be progressively enlarged with hard texture, uneven surface, often with nodules of different sizes, blunt and uneven edges, and often with different degrees of pressure pain. When liver cancer protrudes under the right costal arch or saber process, the epigastrium may show localized elevation or fullness. Jaundice: It usually appears in the late stage of liver cancer, mostly as obstructive jaundice, and a few as hepatocellular jaundice. The former is often caused by tumor compression or invasion of bile ducts or extrahepatic lymph node enlargement compressing bile ducts, while the latter can be caused by extensive infiltration of cancerous tissues in liver or chronic liver disease loss. Signs of cirrhosis: If the disease develops on the basis of decompensated cirrhosis, it can be manifested as rapidly increasing and difficult to treat peritoneal fluid, multiple leakage of peritoneal fluid, bloody peritoneal fluid caused by hepatocellular carcinoma invading peritoneum or breaking into the peritoneal cavity. It may be caused by severe infection or coagulation factor deficiency. Systemic manifestations: progressive wasting and fever, lack of appetite, weakness, malnutrition, and cachexia, etc. If metastases to the lung bone brain lymph nodes chest cavity, etc., can produce corresponding symptoms. Some patients present with symptoms of metastases as the first time. Concomitant cancer syndrome: a group of syndromes may appear due to metabolic abnormalities of the cancer itself or endocrine metabolism abnormalities of liver cancer patients, such as spontaneous hypoglycemia, erythrocytosis, other rare ones include hypercalcemia, hyperlipidemia and carcinoid syndrome. Therefore, we cannot rely on the symptoms to determine whether we are in the early stage of liver cancer, and we must have regular examination to detect liver cancer early.