Edema (nephrotic syndrome) is mainly manifested by high edema, so it can be treated according to the “edema” in Chinese medicine. In general, the initial symptoms are mostly caused by the presence of evil but not the failure of positive qi, so the treatment can be based on the symptoms (water-dampness); in the long run, the positive deficiency and evil reality are mixed, so the treatment should pay attention to the original deficiency (deficiency of the three organs of the lungs, spleen and kidneys) and the difference of the symptoms (water-dampness, damp-heat with qi stagnation and blood stasis), so that the symptoms can be treated together to achieve curative effects. 1.Treating edema with both the symptoms and the root cause Where edema starts, the course of the disease is relatively short, and facial edema is very serious, it can be treated from the lung, and it is advisable to promote the lung and move water, such as the formula of Yue Maiden Plus Art Tang, Ma Gui Wu Pi Drink, etc. If the edema is highly edematous and does not subside for a long time, and the disease is suddenly combined with external fever or upper sensory cough, then it is not a bad time to use the agent of freeing the lung qi and seepage, and the amount of urine suddenly increases, so that the edema of the whole body subside. For those who have high edema and are suffering from spleen and kidney yang deficiency, we can use the Spleen Drink for those who have spleen yang deficiency and Jisheng Kidney Qi Pill for those who have kidney yang deficiency. However, while warming and promoting percolation, we must supplement with Mu Xiang, Betel nut, Hou Pu, Da Belly Skin, Chen Pi and Shen Xiang to help Qi transformation, which can significantly increase the urine volume. And highly edematous, ascites is obvious, no obvious Yang deficiency, and abdominal distension, are better to move Qi and water, light with large orange peel soup, heavy with the water guide Poria soup, can make the urine volume increased, edema gradually subside. The most ideal treatment for nephrotic syndrome is the combination of Chinese and Western medicine. We have developed a systematic treatment routine and effective prescriptions to reduce proteinuria, eliminate edema, protect kidney function, significantly reduce hormone side effects, prevent hormone dependence and reduce recurrent attacks, which have improved clinical efficacy: ① High-dose hormone treatment: prednisone 1mg/kg/d for adults, taken daily in the morning, for 8 weeks-12 weeks. 12 weeks. In recent years, our department has switched to methylprednisolone 40-80mg/d fine drops, which has shortened the hospitalization days and improved the efficacy with less side effects. This stage is often manifested as the evidence of yin deficiency and fire, the treatment should be nourishing yin and lowering fire, the formula with Zhi Bai Di Huang Tang plus reduction: Zhi Mu, Huang Bai, Sheng Di, Shan Yao. ②Hormone reduction stage: after 8-12 weeks, reduce 10% of the original dose every 1-2 weeks to 20mg/d, pay attention to slow reduction to prevent rebound, during the process of hormone reduction, clinical manifestations often transform from yin deficiency to qi deficiency, and present the evidence of both qi and yin deficiency. During this period, Chinese herbal medicine should be increased to benefit the qi and kidney to facilitate the withdrawal of hormone and consolidate the therapeutic effect, such as gradually adding: princeton ginseng, astragalus, eucommia, Chuanjiao, etc. (3) Maintenance treatment stage: the minimum effective dose is used as the maintenance amount, and 0.5-1 year is taken again. In this period, the emphasis is on relapse prevention, and adults focus on warming the kidneys, and Chinese herbal medicines are added to benefit qi and nourish yin and nourish the spleen and kidneys, such as astragalus, prince’s ginseng, raw earth, wolfberry, codonopsis, bone marrow, cistanches, etc. 3, “long illness into the Luo”, blood circulation to remove blood stasis Kidney syndrome patients have a long course of disease, “long illness into the Luo”, can make the patient’s qi and blood flow is not smooth, and patients mostly have edema, edema for a long time, water stagnation in the meridians, can make the kidney complex paralysis, blood stasis within. At the same time, the patient is highly edematous, with high blood lipids and in a state of hypercoagulation. Therefore, herbs must be added to activate blood circulation and remove blood stasis. Commonly used drugs include Chuanxiong, Tao Ren, Hong Hua, Di Long, Quan Yin, Dan Shen, Ze Lan, Da Huang, etc. 4.Fix the surface to protect the body and prevent colds For patients with nephrotic syndrome, the disease often recurs and worsens because of upper respiratory tract infections, therefore, it is an extremely important link for patients to pay attention to the prevention of colds. If the patient is weak and prone to colds, add Yu Ping Feng San to strengthen the surface and protect the body to prevent colds.