A positive HPV51 does not indicate cervical cancer. Because HPV51 is a high-risk HPV infection clinically, it can lead to cervical cancer if the infection is persistent. However, about 75%-80% of patients with high-risk HPV infection have transient infection, which does not cause lesions to the cervical epithelium. Only 20% of patients with persistent infection cause lesions to the cervical epithelium. It takes about 2-3 years from the time of high-risk HPV infection to the time of lesioning. Therefore, when a high-risk HPV infection is detected, a colposcopy must be done first, mainly to find out whether lesions have already occurred in the cervical epithelium.