“Doctor, I am 56 years old and have been menopausal for half a year. In recent months, I have been suffering from frequent insomnia, night sweats and easy anger. My husband and children have complained that I have an odd temper. …… I have also heard about hormone therapy, but I am afraid that estrogen supplementation will give birth to cancer, so I have been holding back, but the symptoms of menopause are getting more and more powerful. ……” Just a few sentences reflect the current Chinese These few words reflect the voices of 160 million middle-aged and elderly women in China who are suffering from the confusion and pain of menopause. Most of them regard menopause as a natural physiological phenomenon and do not need to intervene, just let it happen; a few women seek help and treatment, they may know that menopausal symptoms need hormone treatment, but they are afraid of “talking about hormones” – they are afraid that using hormones will make them fat, or even make them feel like they are in a bad mood. Now, let’s start with the relationship between menopause and hormone therapy. Menopause is the period when women transition from childbearing age to old age. To be more precise, it should be called menopause, which occurs between the ages of 40 and 55. During this period, the ovaries gradually decline and lose their function. At present, the average age of menopause for women in China is around 50 years old. The factors that determine the age of menopause, in addition to genetic factors, are often related to nutrition, fertility, obesity, lifestyle, etc. Menopausal women can suffer from a variety of health problems due to the decrease in estrogen. Recent diseases such as menopausal syndrome, medium and long term diseases such as genitourinary tract atrophy, osteoporosis, cardiovascular diseases and various metabolic syndromes. The menopausal syndrome is an autonomic disorder caused by endocrine changes. It is an important disease that affects the quality of life of perimenopausal women, with an onset of years or longer. In severe cases, the symptoms can recur 1 to 10 times a day, each lasting from 1 to 15 minutes, seriously affecting life and work. Other common symptoms include head weight, insomnia, irritability, irritability, agitation, depression, memory loss, lack of concentration, general tiredness and fatigue, joint pain, itchy skin, abnormal skin sensations, etc. The various symptoms of women in the subsequent menopause appear gradually. The number and severity of symptoms varies greatly among individuals, with approximately 75% of women experiencing menopausal syndrome, but only 10% to 25% of patients with severe symptoms require treatment. Atrophy of the genitourinary tract. Patients may present with vaginal tenesmus, pain, tenderness and difficulty in urination, recurrent vaginitis and urinary tract infections. Patients with osteoporosis have external manifestations such as back pain, shortening of height, hunching over, and their danger of being prone to fractures, which affects the quality of life of women. These diseases and problems are caused by the decrease of estrogen, so the use of estrogen and progestin therapy after menopause was established in the early 1960s; after the 1980s, it was confirmed that estrogen can prevent osteoporosis; the addition of Bihormone can eliminate the risk of endometrial cancer caused by estrogen alone Through decades of clinical heart use research, the International Menopause Society organization reached the following consensus on hormone therapy during menopause: 1. Postmenopausal women with menopausal symptoms and high risk factors for osteoporosis. Advocate the early application of hormone therapy, early use, the benefits outweigh the disadvantages. 2.Women within the range of symptoms should be evaluated for pros and cons, and as long as the benefits outweigh the risks, there is a value of application. 3.Apply the lowest effective physiological dose according to individual differences, choose different drug types and routes of use, and select individualized kineto therapy programs. 4.Post hormone replacement therapy can not only relieve menopausal symptoms, prevent bone loss and fracture, but also provide further protection to cardiovascular and brain. 5. It is safe to apply it continuously for 5 years after menopause, and physical examination is conducted at least once a year during the medication period to assess individual risk factors and benefits, and the length of treatment course is decided according to the assessment and individual needs. According to the above dosing principles. For women with more typical menopausal symptoms and those who are willing to undergo hormone replacement therapy, they can consider applying hormone therapy, but they must be carefully examined by a doctor before judging whether they can use the medication, choosing an individualized treatment plan, and deciding the length of time to take the medication through close and regular follow-up. In conclusion, not all women need hormone therapy, but hormone therapy will enable some women to go through menopause healthily and happily, and some women will always exude youthfulness and maintain a high quality of life.