The best time of the day to take probiotics is in the morning on an empty stomach or with a meal, and the water temperature should not be too high when taking them. Probiotics are a kind of active microorganisms that are beneficial to human body and are helpful to relieve diarrhea, constipation, flatulence, indigestion and other symptoms caused by intestinal flora imbalance. Taking probiotics in the morning on an empty stomach is good for probiotics to reach the site of intestinal colonization smoothly and establish normal flora, which helps restore normal digestive function. However, it should be noted that if the water temperature is too high, the live bacterial preparation will be easily affected and the corresponding effect will not be achieved, so you must pay attention to the water temperature when taking it. If you are taking probiotics and using antibiotics at the same time, you should pay attention to the interval of about 2 hours. Probiotics are beneficial to the human body, but not the more the better, and should not be excessive intake and supplementation of probiotics, scientific and reasonable use, in order to truly beneficial to the human micro-ecological balance.