A similar question often asked by many patients and family members is how to heal a foot wound that never recovers. We should know that there must be a reason for everything, and we must first find the cause of the wound not healing, and then treat it symptomatically. Today I will briefly introduce a few factors that affect healing. First, the patient’s high blood sugar. Wounds that do not heal due to elevated blood sugar are more complex and invisible to the naked eye, but they involve cells, tissues, and other aspects of the problem. One of the end results, for example, is that high blood sugar can easily lead to a serious imbalance in osmotic pressure inside and outside the cells, which reduces the activity of the cells that repair and heal wounds, and reduces the healing ability. Second, infection. Infection is one of the main reasons for hindering wound healing. Infected necrotic tissues cover the surface of healthy tissues and can prevent their normal metabolism. Above a large number of germs continue to eat normal cells and tissues, the wound will continue to deteriorate, not to mention the healing seal. Third, the lower extremity ischemia. In particular, dry gangrene of the diabetic foot is typical of ischemic gangrene of the lower extremities, and some mixed types of gangrene will also be ischemic. We also know that the healing of the wound also requires an adequate supply of blood, drugs, but the lower limb ischemia leads to a decrease in blood oxygen saturation, can not supply to the wound needs, the speed of healing will decline. Fourth, the overall physical condition of the patient will also affect the wound healing. For example, some patients have low protein and anemia, which will also affect the body’s self-healing function. Some patients also suffer from cardiovascular disease, hemiplegia sequelae, age-related decompensation, other diabetic complications, etc., which affect each other, and ultimately affect the wound healing. V. Psychological factors. I don’t know if you have heard of such a thing, a person learned that his body collapsed within a short period of time after learning that he had cancer, which is mainly due to psychological factors. The same is true for diabetic foot patients. If you look at it objectively and rationally, don’t be too nervous and afraid, it will help a lot for the recovery of the wound. Of course, the above is only the situation that we encounter more often, in addition to diet, exercise, etc., these conditions can affect the wound healing. However, it is important to know that each patient’s situation is different, and the cause of the disease is not the same, so in the clinical diagnosis and treatment must be based on the actual situation of the patient to develop a treatment plan, and strive to personalized, in order to achieve the purpose of allowing patients to heal as soon as possible.