Nervous breakdown can cause headaches. Patients with neurasthenia are mainly characterized by poor sleep, mental tension and stress, and patients can also experience dizziness, nausea and vomiting. Patients are often accompanied by anxiety, depressive state. Headache caused by neurasthenia is mainly caused by relaxing, reducing stress, improving sleep, appropriately participating in some physical exercise, ensuring sufficient sleep time, and developing good habits, such as getting up on time for sleep, which may reduce the symptoms, and also listening to some gentle music before sleep, which can help improve sleep and reduce headache. If necessary, oral glutamate treatment can be given. In severe cases, oral sedatives, such as diazepam, eszopiclone or alprazolam, can also be given. Patients with combined anxiety and depression can be treated with appropriate anti-anxiety and antidepressant drugs. The commonly used clinical anti-anxiety drugs mainly include tandospirone, buspirone, lorazepam, and antidepressants mainly include citalopram.