The palms of liver cancer patients are getting redder and redder, and this phenomenon is called liver palm, which mainly manifests as redness on both sides of the large and small fissures of both hands. The appearance of liver palm is due to the effect of cancer cells of liver cancer patients, liver function will be damaged, the function of liver to inactivate estrogen will be reduced, and the level of estrogen in the body will be increased, and one of the clinical manifestations of increased estrogen level is local capillary dilation and congestion, which results in the redness of palms between large and small fissures. As liver cancer progresses, liver function continues to decline and estrogen accumulates more and more in the body, then the palms of hands will become more and more red. If the palms of liver cancer patients become redder and redder, it indicates the aggravation of the disease, which should attract the attention of clinicians and promptly carry out relevant examination and treatment.