Among the many treatment methods for liver cancer, the main ones that can achieve radical effect are hepatectomy and liver transplantation. Ultrasound interventions including percutaneous anhydrous alcohol injection, percutaneous radiofrequency ablation, microwave ablation, thermal therapy such as high-energy focused ultrasound and argon helium knife cryotherapy, etc., although some smaller hepatocellular carcinomas can achieve radical effect, are still partly controversial and need further large-scale randomized clinical control studies. TACE, Chinese herbal medicine treatment, biological therapy, radiation therapy and chemotherapy are all non-radical treatments. Although liver transplantation is theoretically more radical, it cannot be the first choice for liver cancer treatment due to many problems such as tight liver supply, high cost of liver transplantation, indications for liver transplantation, the need for lifelong anti-rejection drugs and immunosuppression after liver transplantation. Hepatectomy has good immediate and long-term therapeutic effects on liver cancer, which has been confirmed by numerous studies at home and abroad and has become the consensus in the industry. Moreover, compared with liver transplantation, hepatectomy has many advantages such as more economical, wider indications, and no need for too many adjuvant treatments after surgery, therefore, it has become the preferred treatment method for liver cancer.