The urethral warts are caused by the human papilloma virus (HPV) infection in the urethral area of the epidermis, benign growths, is the most common sexually transmitted diseases worldwide. The results have been less than ideal. In the past, the general laser, freezing and surgical treatment, but the treatment of patients painful, easy to mu plague ping Li refers to the more superfluous pancreatic Ivana bump sinking: 郏 urethral stenosis, as well as sexual dysfunction and other adverse reactions. Photodynamic therapy is the combined application of photosensitizers (Ira. The actual PDT includes the application of photosensitizer, the aggregation of photosensitizer molecules in the lesion tissue and the exposure to a suitable visible light source. 2, low recurrence rate: ALA-PDT treatment of condyloma acuminata removal rate of 98.42%, but the recurrence rate is significantly lower than freezing, laser, surgery, drug treatment. The main target of photodynamic therapy is the lesion tissue in the light area, and the damage to the normal tissue around the lesion is slight, this selective killing effect is difficult to achieve by many other treatments. 5, can protect the function of important organs: for the urethral part of the condyloma acuminata, the application of photodynamic therapy in the effective treatment of condyloma acuminata, as far as possible to reduce the damage to the pathogenic organs, so that the urethral wound healing is not affected, to maintain the integrity of the organ shape and normal physiological function. Phase III clinical trials of this project showed that: ALA – Photodynamic therapy for acromegaly in the urethral region has a wart clearance rate of 98.42%, but the recurrence rate is significantly lower than that of freezing as well as laser and surgical treatment. In terms of safety, the incidence of adverse reactions of ALA-PDT therapy was significantly lower than other traditional physical therapy methods, indicating that ALA-PDT therapy is safe and effective in treating warts, with less damage, high cure rate and low recurrence rate, and is worth promoting in clinical application. ALA-PDT therapy has a high clearance rate and low recurrence rate for urethral warts, and has the advantages of less trauma, no pain, and fewer adverse reactions, which is the most ideal treatment option for urethral warts and has unique advantages in clinical application.