Liver cancer is one of the most common malignant tumors worldwide, and it is a serious threat to the health of the general public. Since most patients are already in the “middle to late stage” when they are diagnosed, which makes treatment very difficult, it is especially important to understand the early scientific prevention methods of liver cancer. Approach 1: Hepatitis B vaccination before marriage Evidence-based medical evidence shows that chronic viral hepatitis is the most important causative factor of liver cancer in China. Epidemiological surveys have found that the HBsAg positivity rate of liver cancer patients can reach 90%; other scientific studies have shown that the probability of developing liver cancer among HBsAg positive people is significantly higher than that of HBsAg negative people. Therefore, for a country with hepatitis like China, if we can do a good job in prevention – ensuring that we do not have hepatitis B – the chance of liver cancer will be significantly reduced. Some data show that about 70% of young adults with viral hepatitis B in China are currently infected through the “mother-to-child” channel in early life, and there is also “horizontal transmission” between husband and wife. Therefore, prevention of hepatitis should start before marriage. In recent years, the “premarital hepatitis B vaccination” has been very effective in interrupting the transmission of hepatitis B virus. On this basis, we also encourage “routine vaccination of newborns against hepatitis B after birth”, and the two methods together will be an effective way to prevent liver cancer. Approach 2: Manage water source Research shows that algal toxins produced by blue-green algae growing in ponds are likely to be related to the occurrence and development of liver cancer. Therefore, we encourage people to drink deep well water and tap water when available, and to disinfect drinking water before drinking to prevent contamination of water sources. Approach 3: Manage food Aflatoxin B1, a metabolite of aflatoxin, has a strong carcinogenic effect, and studies have shown that aflatoxin B1 is closely related to the occurrence of liver cancer. Aflatoxin is mainly found in moldy corn, peanuts and other foods. Therefore, here we call on food supervision departments to take active and strong measures to prevent moldy food from entering the market, and strictly prohibit businesses from adding preservatives, whitening and coloring toxic and harmful chemical agents in food or food; at the same time, in our daily lives we must also ensure that the food is fresh. Approach 4: Quit drinking Alcohol abuse can make the damage to the liver gradually progress from fatty liver to alcoholic cirrhosis, which in turn leads to the occurrence and development of liver cancer on the basis of cirrhosis. On the other hand, studies have shown that alcohol abuse and chronic viral hepatitis have a synergistic effect on the occurrence and development of liver cancer, and can accelerate the development of liver cancer and significantly reduce people’s quality of life and life expectancy. Therefore, it is especially important for patients with chronic viral hepatitis and liver cirrhosis to drink less alcohol or even no alcohol. Doctor’s tip: According to statistics, a significant number of hepatitis patients are accompanied by psychopathology. If the psychological guidance and treatment are neglected, coupled with the poor psychological quality of some patients, they are prone to fear, anxiety, depression and other adverse emotions. Such emotions persist for a long time, which will lead to a series of changes in the nervous system, endocrine system and immune function, which further promote the growth and development of tumor. Therefore, we suggest family members to communicate with patients frequently to keep them in a positive and healthy state of mind. At the same time, we encourage people to take appropriate amount of physical exercise at the right time to enhance the immune function of the body, thus avoiding the cancerous transformation of liver cells and preventing liver cancer.